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. 2018 Oct 12;92(21):e00426-18. doi: 10.1128/JVI.00426-18

FIG 12.

FIG 12

A putative model of the role of VP30 phosphorylation in MARV transcription. The phosphorylated form of VP30 (red, left) binds to NP and VP35 and suppresses transcription. The dephosphorylated form of VP30 (green, right) is dissociated from NP and VP35 and does not inhibit transcription. The phosphorylated form of VP30 may work as a repressor of MARV polymerase by associating with NP and VP35. Treatment of cells with 1E7-03 prevents dephosphorylation of VP30 by PP1 that results in suppression of MARV transcription.