FIG 8.
Interactions between RdRp and NTPase. (A) NTPase interacts with RdRp through RdRp's finger subdomain, near the template entrance. (B) NTPase and RdRp rotated 90° in opposite directions to show the triangle-shaped interface. (C) Same view as in panel B, showing positive (blue), neutral (white), and negative (red) Coulomb potentials. (D) Same view as in panel B, showing high hydrophobicity (orange) and high hydrophilicity (blue). (E) NTD-finger interaction in the region boxed in panel C. (F) NTPase domain-finger interaction in the region boxed in panel A. (G) CTD-NTD interaction in the region boxed in panel D.