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. 2011 Jan 25;300(4):E650–E660. doi: 10.1152/ajpendo.00440.2010

Fig. 3.

Fig. 3.

Effects of ORX, TE, or graded doses of TREN on weekly body weight (BW) change (A) and total BW change (B) corrected for food consumption. Rats received ORX vs. sham surgery and were treated with intramuscular injections of vehicle, TE (7.0 mg/wk), or TREN (1.0, 3.5, or 7.0 mg/wk) for a period of 29 days. BW gain was reduced by ORX on day 3, and this reduction was initially prevented by all drug treatment groups. At euthanization, the BW change corrected for food intake was similarly reduced in all ORX groups compared with SHAM. Values are means ± SE; n = 9–10/group. Letters indicate differences from respectively labeled groups at P < 0.05 or *P < 0.01 (avs. SHAM; bvs. ORX; cvs.ORX + TE; dvs. ORX + low TREN; evs. ORX + mod TREN).