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. 2018 Oct 2;2018:6091934. doi: 10.1155/2018/6091934

Figure 4.

Figure 4

Evaluation of the toxicity of Bixa orellana extracts (BoHE and BoEA) in C57BL/6 mice 4 h after induction of peritonitis. Saline: animals treated with 0.9% saline solution (1 mL/kg) without Mabs inoculation (negative control); Mabs: animals treated with 0.9% saline solution (1 mL/kg) and inoculated with Mabs; Dexa: animals treated with 5 mg/kg dexamethasone and inoculated with Mabs; BoHE 50 mg/kg: animals treated with 50 mg/kg BoHE and inoculated with Mabs; BoHE 150 mg/kg: animals treated with 150 mg/kg BoHE and inoculated with Mabs; BoEA 50 mg/kg: animals treated with 50 mg/kg BoEA and inoculated with Mabs; BoEA 150 mg/kg: animals treated with 150 mg/kg BoEA and inoculated with Mabs. Column (A): esophageal/stomach transition area with no significant histological changes. Column (B): liver histology has a normal appearance. Column (C): kidney histology has a normal appearance. H&E stain, ×100.