Table 2.

Statistical analysis of evoked EUS EMG responses in naive animals before and after drugs

Naive Animals	Without Drug	8-OH-DPAT	8-OH-DPAT + WAY100635
n	9	9	7
Inhibition of EUS activity, s	39 ± 6	33 ± 4	61 ± 16†
Latency to the beginning of inhibition, s	29 ± 4	22 ± 3	23 ± 3
Duration of EUS bursting, s	18 ± 2	21 ± 3	19 ± 3
Frequency of EUS bursting, Hz	1.7 ± 0.3	1.8 ± 0.3	0.3 ± 0.1†
Amplitude of EUS bursting, mV	0.15 ± 0.03	0.23 ± 0.06*	0.11 ± 0.03
AUC of EUS bursting, mV/s	0.33 ± 0.08	0.67 ± 0.04*	0.16 ± 0.06†

Inhibition of EUS EMG activity includes the duration of EUS bursting. WAY100635 (0.3 mg/kg iv) was given after 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT; 0.5 mg/kg iv).

^*†P < 0.05, significant change compared with the recordings before drug administration.