Table 3.
Management of infections in liver transplant recipients
| Population/ infection | Risk factor and type of infection | Management | Ref. |
| Liver transplant candidates/all infections | Donor-derived. Active/latent infections. Vaccine-preventable infection. | Donor screening. Careful patient history and physical examination. Identification of infections requiring therapy. Immunization. | [160-165] |
| Liver transplant recipients/bacterial | Nosocomial infections (ICU, invasive devices). Recurrent infections (anatomical defects). Immunosuppression. | Peri-transplant antibiotic prophylaxis (< 48 h). Prompt diagnostic workup (uncommon presentations, opportunisms). Source control when needed. | [76,83,160] |
| Liver transplant candidates and recipients/MDRO | Colonization (MRSA, VRE, CRE) linked to increased risk of infections. Risk of transmission between patients and across wards. | Surveillance cultures (CRE, VRE, MRSA) and decolonization (MRSA). Infection control (hand hygiene, isolation, contact precautions). | [102,112,164] |
LT: Liver transplantation; ICU: Intensive care unit; MDRO: Multidrug-resistant organisms; MRSA: Methicillin-resistant Staphylococcus aureus; VRE: Vancomycin-resistant enterococci; CRE: Carbapenem-resistant Enterobacteriaceae.