Table 1.

Overview of microfluidic devices to enable sorting of C. elegans.

Device	Method	Throughput	Sorting Capabilities	References
PDMS single channel device	Electrotaxis	78 worms per minute	Specific developmental stages and adults; mutants from wild type	Rezai et al., 2010 and 2012 [9,10]
Agarose gel box containing a single long channel	Electrotaxis	Unknown	Adults of different age; mutants from wild type	Maniere et al., 2011 [11]
PDMS device containing interconnected mazes	Flow filtration	200–300 worms per minute	Larvae from adults	Solvas et al., 2011 [12]
PDMS multichannel device	Electrotaxis	4 worms per minute	All stages including adults	Han et al., 2012 [13]
PDMS micro-pillar device	Flow filtration	130–180 worms per minute	All stages including adults	Ai et al., 2014 [14]
PDMS device containing optical fiber and laminar flow switch	Fluorescence filtration	12 worms per minute	Fluorescent animals	Yan et al., 2014 [15]
PDMS-Agarose fan-shaped device	Electrotaxis	56 worms per minute	L2–L4 larvae and adult; size-based separation	Wang et al., 2015 [16]
PDMS device containing adjustable filter	Pressure-based filtration	200 worms per minute	Certain developmental stages	Dong et al., 2016 [17]