Skip to main content
. 2018 Aug 22;18(3):157–170. doi: 10.3727/105221618X15242506133273

Figure 7.

Figure 7

socs3a homozygous mutants exhibit a mild but significant defect in BEC number during LPC-driven liver regeneration. (A) Confocal projection images showing Tp1:H2B-mCherry (red) and Bhmt (gray) expression in the regenerating livers of wild-type and socs3a mutants at R6h. Numbers in the top right corner indicate the proportion of socs3a mutants exhibiting a reduced number of BECs at R6h (n = 6/22). Quantification of the percentage of Bhmt+ cells among H2B-mCherry+ cells is shown. Arrows point to Bhmt+ and H2B-mCherry+ cells. Arrowheads point to Bhmt- and H2B-mCherry+ cells. (B) Confocal projection images of wild-type and socs3a mutant regenerating livers exhibiting Tp1:H2B-mCherry (red) and Bhmt (gray) expression at R24h. (C) Confocal projection images showing Tp1:H2B-mCherry (red) and Alcam (green) expression in the regenerating livers of wild-type and socs3a mutants at R24h. Quantification of the number of BECs (H2B-mCherry/Alcam double-positive cells) per liver area is shown. Arrows point to H2B-mCherry/Alcam double-positive cells. Dashed lines outline regenerating livers. Scale bars: 20 μm; error bars: ± SEM.