Table 2. Leukogram and platelet count after intraperitoneal injections of phenylhydrazine (20 mg/kg bw, for two consecutive days) and oral administration of Beta vulgaris leaf and stalk extract (BVE-LD, BVE-SD, 100 and 200 mg/kg b wt., for 12 consecutive days), compared to those after the standard ferrous ascorbate+folate (13.5+0.135 mg/kg bw, for 12 consecutive days) and normal control (saline).
| Days | Parameters | Groups | ||||
|---|---|---|---|---|---|---|
| Control | Diseased | Standard | BVE-SD | BVE-LD | ||
| 0 | WBC (109/L) | 17.47±1.21 | 17.37±1.28 | 17.56±1.39 | 17.07±1.28 | 17.30±1.35 |
| Lymphocytes (%) | 69.67±3.18 | 69.03±3.79 | 69.47±2.95 | 70.31±3.21 | 70.10±2.93 | |
| Mid-sized (%) | 0.73±0.36 | 0.81±0.36 | 0.70±0.32 | 0.74±0.34 | 0.74±0.32 | |
| Gran (%) | 12.26±1.10 | 11.33±0.73 | 11.71±0.92 | 12.03±1.13 | 12.53±1.21 | |
| PLT (109/L) | 455.7±7.5 | 453.1±9.9 | 452.6±8.9 | 461.2±9.4 | 466.7±8.63 | |
| 4 | WBC (109/L) | 17.51±1.39 | 25.63±2.88+ | 19.13±1.24* | 22.03±2.12* | 20.13±1.85* |
| Lymphocytes (%) | 69.43±2.86 | 80.35±2.76+ | 74.69±2.75* | 78.43±2.07 | 75.96±2.30* | |
| Mid-sized (%) | 0.74±0.41 | 1.02±0.15 | 0.74±0.39* | 0.75±0.31* | 0.77±0.34* | |
| Gran (%) | 12.30±1.05 | 20.31±1.36+ | 15.03±0.91* | 18.34±0.78 | 17.06±0.98* | |
| PLT (109/L) | 459.3±6.96 | 479.34±8.09 | 464.35±7.63 | 465.5±7.85 | 464.2±6.53 | |
| 8 | WBC (109/L) | 17.53±1.35 | 23.08±2.07+ | 18.07±1.30* | 20.01±1.12* | 17.91±1.19* |
| Lymphocytes (%) | 70.33±2.84 | 77.23±2.03+ | 73.17±2.09* | 76.04±2.06 | 73.93±2.10* | |
| Mid-sized (%) | 0.78±1.39 | 1.30±0.19 | 0.83±0.34* | 0.77±0.23 | 0.80±0.25* | |
| Gran (%) | 12.17±0.97 | 18.07±1.01+ | 13.71±1.09* | 17.10±0.78 | 15.17±0.91* | |
| PLT (109/L) | 458.67±7.3 | 473.4±7.8 | 459.6±8.5 | 465.1±8.5 | 462.3±7.8 | |
| 12 | WBC (109/L) | 17.60±1.42 | 20.03±2.29 | 17.56±1.18* | 18.53± 1.63* | 17.70±1.72* |
| Lymphocytes (%) | 70.61±2.76 | 75.11±2.71 | 72.34±2.06 | 74.10±2.10 | 72.16±2.73 | |
| Mid-sized (%) | 0.79±0.23 | 0.98±0.40 | 0.78±0.24 | 0.78±0.23 | 0.83±0.23 | |
| Gran (%) | 12.37±0.93 | 17.33±1.03+ | 13.06±0.76* | 16.06±0.88 | 13.46±0.84* | |
| PLT (109/L) | 457.2±7.8 | 470.7±7.5 | 454.3±12.3 | 461.7±8.6 | 455.8±9.6 | |
Data are reported as means±SE; n=6. WBC: white blood cells; Mid-sized: (monocytes); Gran: (granulocytes: neutrophils, eosinophils, basophils); PLT: platelet counts. +P<0.05 compared to control; *P<0.05 compared to diseased (ANOVA).