Figure 1. Propofol attenuated cecal ligation and puncture (CLP)-induced acute kidney injury in mice. Twenty-four hours after CLP surgical operation, renal histology (magnification 200×; A) and injury score (B) were performed in the kidneys from mice with or without propofol treatment. Renal expression of neutrophil gelatinase associated lipocalin (NGAL) mRNA (relative to the controls) was measured by RT-qPCR (C) and verified by agarose gel electrophoresis analysis (D). Data are reported as means±SD (n=12 per group). *P<0.05, **P<0.01, ***P<0.001 compared with the control group; #P<0.05 compared with the CLP group (ANOVA). nd: not detected.
