Table 2. Effects of propofol on hepatic and renal function in cecal ligation and puncture (CLP)-operated or sham-operated mice.
| Sham | CLP | Propofol | Propofol+CLP | |
|---|---|---|---|---|
| CCL-2 (pg/mL) | 136.49±15.27 | 321.67±48.34* | 151.82±16.37 | 198.61±31.47# |
| GOT (U/L) | 67.49±7.15 | 432.67±78.93* | 73.83±10.52 | 173.56±25.73# |
| GPT (U/L) | 38.47±5.35 | 205.71±36.72* | 45.84±6.21 | 75.49±13.51# |
| BUN (mmol/L) | 5.78±0.62 | 17.27±2.31* | 4.89±0.71 | 9.12±1.68# |
| Cre (μmol/L) | 4.31±0.51 | 54.65±10.95* | 5.36±0.47 | 20.61±4.22# |
Data are reported as the means±SD. *P<0.05 compared with the Sham group; #P<0.05 compared with the CLP group (ANOVA). GOT: glutamic oxaloacetic transaminase; GPT: glutamic pyruvic transaminase; BUN: blood urea nitrogen; Cre: creatinine.