Table 2.

Antifungal activity of A. hirtifolium and A. sativum against clinical isolates of C. tropicalis as assessed by broth microdilution assay after 24 hr incubation at 35°C.

Isolates/ Extracts	A. hirtifolium *			A. sativum *			Fluconazole **
Aqueous
	MIC 50	MIC 90	MFC	MIC 50	MIC 90	MFC	MIC 50	MIC 90	MFC
Ct ATCC	6.27±0.32	11.28±1.12	12.54±0.56	11.27±0.78	21.12±1.22	24.12±0.98	0.80±0.09	2.50±0.20	3.30±0.25
Ct1	6.25±0.45	11.26±1.31	12.51±1.09	10.25±1.45	21.26±1.33	25.51±1.22	0.60±0.02	2.30±0.10	3.20±0.23
Ct2	6.80±0.66	12.24±0.89	13.60±1.11	11.11±0.98	22.24±0.98	23.60±1.33	0.60±0.10	3.30±0.20	4.40±0.32
Ct3	6.82±0.56	12.27±0.99	13.64±1.15	10.25±1.56	22.27±0.99	23.64±1.23	0.50±0.00	2.60±0.30	3.20±0.24
Ct4	6.57±0.45	11.82±0.67	13.14±0.98	10.57±1.45	21.82±0.79	25.14±1.98	0.70±0.08	3.50±0.20	4.50±0.33
Ct5	6.55±0.44	11.80±1.12	13.10±1.09	9.55±0.99	22.80±1.22	23.10±1.45	0.50±0.02	2.50±0.30	3.50±0.33
Ct6	6.36±0.29	11.44±1.18	12.72±1.45	11.23±0.99	21.22±1.22	24.14±1.55	0.60±0.10	3.60±0.10	4.40±0.33
Ct7	6.80±0.48	12.24±1.56	13.60±1.12	12.80±1.48	22.24±1.55	25.55±1.45	0.50±0.20	3.50±0.40	4.50±0.35
Ct8	6.4±0.34	11.55±1.13	12.84±0.96	10.42±0.98	21.33±1.33	24.33±1.96	0.70±0.10	2.50±0.20	3.50±0.42
Ct9	6.75±0.69	12.15±1.66	13.50±1.03	11.75±1.34	22.15±1.99	25.50±1.44	0.80±0.07	2.90±0.30	3.30±0.25
Ct10	6.57±0.68	11.82±0.99	13.14±0.87	10.57±1.11	21.21±1.99	24.33±1.87	0.50±0.08	3.50±0.10	4.20±0.15
Ethanolic
	MIC 50	MIC 90	MFC	MIC 50	MIC 90	MFC	MIC 50	MIC 90	MFC
Ct ATCC	6.78±0.25	12.20±1.11	13.56±0.99	11.11±1.25	22.09±1.21	23.56±0.78	0.80±0.09	2.50±0.20	3.30±0.25
Ct1	6.30±0.45	11.30±1.34	12.56±1.01	12.22±1.16	21.23±1.55	23.12±1.34	0.60±0.02	2.30±0.10	3.20±0.23
Ct2	6.55±0.33	11.79±1.09	13.10±0.88	11.55±0.78	23.79±1.44	25.33±0.99	0.60±0.10	3.30±0.20	4.40±0.32
Ct3	6.90±0.56	12.42±0.97	13.80±0.98	10.90±0.89	22.42±0.99	23.44±0.77	0.50±0.00	2.60±0.30	3.20±0.24
Ct4	6.25±0.57	11.25±1.13	12.50±0.78	11.25±1.09	23.25±1.08	25.58±1.78	0.70±0.08	3.50±0.20	4.50±0.33
Ct5	6.25±0.22	11.25±0.99	12.50±0.48	11.25±0.98	23.45±1.99	25.11±1.11	0.50±0.02	2.50±0.30	3.50±0.33
Ct6	6.15±0.43	11.07±1.25	12.30±1.13	12.12±1.12	22.21±1.34	23.44±1.44	0.60±0.10	3.60±0.10	4.40±0.33
Ct7	6.25±0.14	11.25±0.58	12.50±0.98	11.25±1.14	23.25±0.99	25.50±0.88	0.50±0.20	3.50±0.40	4.50±0.35
Ct8	6.27±0.59	11.28±0.89	12.54±0.37	12.27±1.13	23.28±0.99	25.46±0.99	0.70±0.10	2.50±0.20	3.50±0.42
Ct9	6.23±0.71	11.21±0.76	12.46±0.76	11.23±0.99	22.21±0.88	25.46±0.89	0.80±0.07	2.90±0.30	3.30±0.25
Ct10	6.35±0.29	11.43±1.01	12.70±0.88	12.45±1.44	23.43±1.67	24.90±0.72	0.50±0.08	3.50±0.10	4.20±0.15

Ct: C. tropicalis.

^*MIC and MFC values are expressed as mg/ml obtained from three independent experiments.

^**MIC and MFC values are expressed as μg/ml obtained from three independent experiments.