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. 2017 Oct 7;8(10):299. doi: 10.3390/mi8100299

Figure 2.

Figure 2

2D Microdevices Utilized to Study Glucose Exposure and the Blood Brain Barrier Under Fluid Flow. (A) Schematic of microfluidic chip for exposing cells to various glucose concentrations under fluid flow; (B) Fluorescent image of endothelial cell morphology and reactive oxygen species spatial distribution under low fluid shear stress; (C) Fluorescent image of endothelial cell morphology and reactive oxygen species spatial distribution under high fluid shear stress; (D) Schematic of μ-Blood Brain Barrier device showing; and (E) fluorescent images of cells cultured inside μ-Blood Brain Barrier device (adapted from Chin et al. [16] and Booth et al. [17]).