Effect of UGBE on TLR4 expression in G/L-challenged liver injury model. (A) Protein expression of TLR4 in the liver. (B) Photomicrographs of TLR4 immunohistochemistry assay: a, control group; b, G/L group; c, G/L + silymarin (150 mg/kg) group; d, G/L + GBE (200 mg/kg) group; e, G/L + UGBE (250 mg/kg) group; and f, G/L + UGBE (500 mg/kg) group. The sample number in each group is 9 (n = 9). Data represent mean ± SEM. ***p < 0.005 compared with control. ##p< 0.01 compared with G/L. ###p < 0.005 compared with G/L. GBE, P. ginseng berry extract; G/L, D-galactosamine/lipopolysaccharide; SEM, standard error of the mean; Sil, silymarin; TLR4, toll-like receptor 4; UGBE, ultrasonication-processed P. ginseng berry extract.