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. 2018 Sep 1;13:233–243. doi: 10.1016/j.omtn.2018.08.019

Figure 1.

Figure 1

miRNAs and lncRNAs in Targeted Therapy with Explicit Targets and Pathways

These pathways mainly comprise the Raf-1/MAPK/IL-6 axis, IL-6/STAT3/NF-κB axis, and PI3K/Akt/mTOR axis, and they center on targets of PTEN, IGF1R, and ERK. Among the ncRNAs involved, miR-7, miR-21, miR-630, and lncRNA UCA1 play important roles.