Table 3:
Percentage change in serum-PFAS concentrations per month during exclusive breast-feeding, partial, and none, as compared to the effect of a 10% increase in ponderal index (PI) and whale intake. All results are adjusted for changes in PI and whale intake.
| Mixed model up to 18 months | Mixed model up to 60 months | ||||||
|---|---|---|---|---|---|---|---|
| PFAS (ng/mL) | Variable | Change | 95%CI | p-value | Change | 95%CI | p-value |
| PFOS | Exclusive | 30.0 | (26.0, 34.0) | <.0001 | 30.5 | (26.4, 34.8) | <.0001 |
| Partial | 3.2 | (0.0, 6.5) | 0.0481 | 0.6 | (−1.5, 2.7) | 0.6021 | |
| None | 1.0 | (−0.1, 2.2) | 0.0738 | −0.9 | (−1.4, −0.3) | 0.0012 | |
| PI | −3.5 | (−7.7, 0.9) | 0.1137 | −0.2 | (−4.8, 4.6) | 0.9251 | |
| Whale | -- | -- | -- | 0.2 | (−17.3, 21.4) | 0.9834 | |
| Sex (boy vs girl) | −4.9 | (−16.0, 7.7) | 0.4248 | −4.3 | (−16.8, 10.0) | 0.5349 | |
| PFOA | Exclusive | 29.0 | (24.8, 33.4) | <.0001 | 29.7 | (25.6, 34.0) | <.0001 |
| Partial | 2.6 | (−0.4, 5.7) | 0.0893 | 0.1 | (−2.1, 2.5) | 0.9059 | |
| None | 0.8 | (−1.0, 2.7) | 0.3909 | −0.6 | (−1.1, 0.0) | 0.0567 | |
| PI | 0.5 | (−4.8, 6.1) | 0.8555 | 5.3 | (0.0, 10.8) | 0.0479 | |
| Whale | -- | -- | -- | −2.8 | (−20.6, 19.1) | 0.7851 | |
| Sex (boy vs girl) | −6.0 | (−20.8, 11.6) | 0.4762 | −2.0 | (−17.6, 16.6) | 0.8206 | |
| PFHXS | Exclusive | −3.6 | (−10.2, 3.4) | 0.2990 | −7.5 | (−12.5, −2.2) | 0.0060 |
| Partial | −2.0 | (−6.5, 2.7) | 0.3972 | 0.9 | (−2.1, 4.0) | 0.5539 | |
| None | −9.1 | (−10.8, −7.3) | <.0001 | −2.4 | (−3.4, −1.4) | <.0001 | |
| PI | 2.7 | (−5.2, 11.2) | 0.5081 | −3.6 | (−11.0, 4.4) | 0.3688 | |
| Whale | -- | -- | -- | 31.9 | (−6.9, 86.8) | 0.1189 | |
| Sex (boy vs girl) | −0.3 | (−17.8, 21.0) | 0.9794 | 10.0 | (−12.3, 38.1) | 0.4071 | |
| PFNA | Exclusive | 21.1 | (15.5, 26.9) | <.0001 | 20.5 | (16.5, 24.6) | <.0001 |
| Partial | 4.3 | (−0.1, 8.9) | 0.0530 | 2.5 | (−0.1, 5.1) | 0.0606 | |
| None | −1.0 | (−2.0, 0.1) | 0.0838 | 0.3 | (−0.1, 0.8) | 0.1581 | |
| PI | −4.9 | (−9.6, 0.2) | 0.0579 | −2.1 | (−6.3, 2.3) | 0.3393 | |
| Whale | -- | -- | -- | 15.3 | (−10.2, 48.2) | 0.2622 | |
| Sex (boy vs girl) | 7.3 | (−11.0, 9.2) | 0.4380 | 8.6 | (−7.7, 27.8) | 0.3160 | |
| PFDA | Exclusive | 17.3 | (11.1, 23.8) | <.0001 | 16.3 | (12.1, 20.7) | <.0001 |
| Partial | 4.7 | (−0.5, 10.1) | 0.0732 | 2.9 | (0.1, 5.9) | 0.0452 | |
| None | 0.6 | (−1.5, 2.8) | 0.5608 | 1.0 | (0.5, 1.5) | 0.0002 | |
| PI | −4.3 | (−9.8, 1.6) | 0.1374 | −1.2 | (−5.7, 3.5) | 0.6022 | |
| Whale | -- | -- | -- | 11.2 | (−11.4, 39.7) | 0.3564 | |
| Sex (boy vs girl) | 0.2 | (−17.5, 21.6) | 0.9869 | 0.1 | (−14.1, 16.7) | 0.9875 | |