Results of the statistical tests that were performed to compare the results of the various methods. pDis analysis (cut-off) was compared to SPIA (cut-off). pDis analysis (all genes) was compared to GSEA, GSA and SPIA (all genes). Each p-value shows whether the ranks and the p-values of the target pathways in proposed method are significantly lower than the reference methods (at 5% significance threshold). The results show that pDis analysis (cut-off) yields significantly better p-values than SPIA (cut-off) for the target pathways. Also, pDis analysis (all genes) yields lower p-values as well as lower ranks compared to GSEA and SPIA (all genes).
