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Corticosteroid release from starting polymer and γ-CD injectable liquid polymer (crosslinked) at concentrations of 1 mg/mL and 100 mg/mL at 37°C. At higher temperatures release is shortened in a drug dependent fashion. Importantly, a measurable delay in release effect is observed in the uncrosslinked state for all drugs. The effect is stronger for the crosslinked formulation. At higher temperatures triamcinolone overcomes the partition effect at this higher temperature.
