. Author manuscript; available in PMC: 2018 Nov 1.

Published in final edited form as: Clin Genet. 2017 Mar 19;92(5):487–494. doi: 10.1111/cge.12974

Table 2.

The SNPs whose association with BP traits was significant in the MEPI-CVD samples

SNP	Chr	Gene	Effect Allele/Other Allele	EAF	Trait	N	BETA	SE
rs2004776	1	AGT	C/T	0.46	SBP	2659	1.38	0.53	0.01
					DBP	2659	0.79	0.32	0.01
					PP	2659	0.59	0.37	0.12
					HTN	2602	0.16	0.07	0.02
					CPASSOC S_Hom	2659/ 2659/ 2602	NA	NA	0.0050
					CPASSOC S_Het	2659/ 2659/ 2602	NA	NA	0.03
rs1458038	4	FGF5	T/C	0.04	SBP	2665	2.25	1.36	0.10
					DBP	2665	0.31	0.83	0.71
					PP	2665	1.94	0.97	0.04
					HTN	2601	0.17	0.17	0.33
					CPASSOC S_Hom	2665/ 2665/ 2601	NA	NA	0.27
					CPASSOC S_Het	2665/ 2665/ 2601	NA	NA	0.35
rs11725861	4	CHIC2	C/T	0.22	SBP	2663	−0.28	0.63	0.66
					DBP	2663	0.66	0.38	0.08
					PP	2663	0.94	0.45	0.04
					HTN	2598	0.14	0.08	0.09
					CPASSOC S_Hom	2663/ 2663/ 2598	NA	NA	0.20
					CPASSOC S_Het	2663/ 2663/ 2598	NA	NA	0.01
rs7726475	5	SUB1/NPR3	A/G	0.01	SBP	2667	−10.41	3.30	0.0016
					DBP	2667	−3.62	2.01	0.07
					PP	2667	−6.79	2.35	0.0039
					HTN	2602	−0.44	0.48	0.36
					CPASSOC S_Hom	2667/ 2667/ 2602	NA	NA	0.03
					CPASSOC S_Het	2667/ 2667/ 2602	NA	NA	0.01
rs11953630	5	EBF1	A/G	0.12	SBP	2665	0.80	0.79	0.31
					DBP	2665	−0.47	0.48	0.34
					PP	2665	1.27	0.56	0.02
					HTN	2600	−0.09	0.10	0.40
					CPASSOC S_Hom	2665/ 2665/ 2600	NA	NA	0.67
					CPASSOC S_Het	2665/ 2665/ 2600	NA	NA	0.02
rs11977526	7	IGFBP-3	T/C	0.33	SBP	2666	1.04	0.59	0.08
					DBP	2666	0.76	0.36	0.03
					PP	2666	0.28	0.42	0.51
					HTN	2601	0.18	0.08	0.02
					CPASSOC S_Hom	2666/ 2666/ 2601	NA	NA	0.01
					CPASSOC S_Het	2666/ 2666/ 2601	NA	NA	0.06
rs11191548	10	CYP17A1	G/A	0.03	SBP	1998	−0.56	1.87	0.77
					DBP	1998	−2.47	1.13	0.03
					PP	1998	1.91	1.32	0.15
					HTN	1984	−0.11	0.25	0.67
					CPASSOC S_Hom	1998/ 1998 1984	NA	NA	0.26
					CPASSOC S_Het	1998/ 1998/ 1984	NA	NA	0.13
rs381815	11	PLEKHA7	T/C	0.28	SBP	2664	0.88	0.57	0.12
					DBP	2664	0.70	0.35	0.04
					PP	2664	0.18	0.41	0.66
					HTN	2600	0.00	0.09	0.99
					CPASSOC S_Hom	2664/ 2664 2600	NA	NA	0.21
					CPASSOC S_Het	2664/ 2664/ 2600	NA	NA	0.18
rs11837544	12	PLXNC1	T/A	0.20	SBP	2665	−1.40	0.65	0.03
					DBP	2665	−0.68	0.39	0.09
					PP	2665	−0.73	0.46	0.12
					HTN	2601	−0.16	0.09	0.07
					CPASSOC S_Hom	2665/ 2665 2601	NA	NA	0.03
					CPASSOC S_Het	2665/ 2665/ 2601	NA	NA	0.12
rs2681492	12	ATP2B1	G/A	0.14	SBP	2661	−1.92	0.74	0.01
					DBP	2661	−1.34	0.45	0.0029
					PP	2661	−0.58	0.53	0.27
					HTN	2598	−0.12	0.10	0.21
					CPASSOC S_Hom	2661/ 2661/ 2598	NA	NA	0.01
					CPASSOC S_Het	2661/ 2661/ 2598	NA	NA	0.02
rs1327235	20	JAG 1	A/G	0.42	SBP	2666	−0.82	0.52	0.12
					DBP	2666	−0.70	0.32	0.03
					PP	2666	−0.12	0.37	0.75
					HTN	2601	−0.10	0.07	0.15
					CPASSOC S_Hom	2666/ 2666/ 2601	NA	NA	0.05
					CPASSOC S_Het	2666/ 2666/ 2601	NA	NA	0.12