FIGURE 5.

Effect of COS treatment on the structure of gut bacterial community in mice. Relative abundance of bacterial community at phylum level (A) genus level (B). Significant differences of the bacteria taxa in mice with or without COS treatments based on Linear discriminant analysis effect size (LEfSe) (C). Significant differences in LDA scores (P < 0.05) were produced among classes (Kruskal–Wallis test) and between subclasses (Wilcoxon’s test). The threshold logarithmic LDA score was 3.6. Significant differences were noted as follows: ^∗P < 0.05.