| Patterson et al. (2010) |
An Evaluation of an Adapted U.S. Model of Pharmaceutical Care to Improve Psychoactive Prescribing for Nursing Home Residents in Northern Ireland (Fleetwood Northern Ireland Study) |
Ireland |
RCT |
Nursing homes |
12 |
22 nursing homes |
22 nursing homes with n = 334 residents, M = 82.7, 73% female intervention group (173) control group (161) |
12 monthly visits from pharmacist to review prescription records of nursing home residents; collaboration of pharmacists with prescribers and patients to improve prescription patterns; pharmacist’s visits assessed the pharmaceutical care needs of each resident to identify potential and actual medication-related problems and reviewed the residents’ medication with the aim of optimizing psychoactive prescription |
Essential characteristics of the clinician, clinician-patient-communication and patient information |
The proportion of residents taking inappropriate psychoactive medications at 12 months in the intervention homes (25/128, 19.5%) was much lower than in the control homes (62/124, 50.0%) (odds ratio 50.26, 95% confidence interval 50.14–0.49) after adjustment for clustering within homes |
| Westbury et al. (2010) |
An effective approach to decrease antipsychotic and benzodiazepine use in nursing homes: the RedUSe project |
Australia |
CT |
Nursing homes |
6 |
25 nursing homes |
25 nursing homes with n = 1,591 residents, not reported intervention group 13 nursing homes control group n = 12 nursing homes |
Consciousness raising two drug use evaluation (DUE) cycles educational sessions promotional materials (newsletters, pamphlets, posters) and educational sessions and materials focused on informing health professionals and participants about risks and modest benefits associated with antipsychotic medications for dementia and benzodiazepines for sleep disturbance and anxiety management in elderly people |
Essential characteristics of the clinician, clinician-patient communication and patient in-formation |
Over the 6-month trial, there was a significant reduction in the percentage of intervention home residents regularly taking benzodiazepines (31.8–26.9%, p < 0.005). For residents taking benzodiazepines at baseline, there were significantly more dose reductions/cessations in intervention homes than in control homes (benzodiazepines: 39.6% vs. 17.6%, p < 0.0001) |