Table 3.
The moderating role of long sleep duration in the relationship between cancer and DM
| Variable | With no interactiona | Unadjustedb | Fully adjustedc | |||
|---|---|---|---|---|---|---|
|
| ||||||
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
|
| ||||||
| Cancer | 2.12 (2.04–2.21) | <0.001 | 2.18 (2.09–2.28) | <0.001 | 1.13 (1.07–1.18) | <0.001 |
| Long sleep (≥9 hours) | 1.71 (1.64–1.79) | <0.001 | 1.77 (1.03–1.11) | <0.001 | 1.32 (1.26–1.39) | <0.001 |
| Interaction (long sleep × cancer) | n/a | n/a | 0.83 (0.74–0.92) | <0.001 | 0.88 (0.78–0.98) | 0.027 |
Notes: Cancer, self-reported physician diagnosis of cancer (all types); long sleep, ≥9 hours of average daily sleep duration over a 24-hour period.
a
Model without interaction variable;
b
unadjusted model where covariates were not adjusted;
c
regression model that adjusted for age, sex, and race/ethnicity. Significant P<0.05; P<0.001.
Abbreviations: DM, diabetes mellitus; OR, odds ratio.