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HR parameters’ dependence on the time and the group of patients. Mixed models with random effects based on two-way ANOVA indicate that there was a significant effect of time (p = 0.0238), group (p = 0.0087) and both group × time (II group after 28-h TSD; III group after 28 and 32-h TSD). Interestingly, both groups reported a decrease of HR during the TSD compared to baseline.
