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Dissociation constants (Kd) values defined by means of BLI for each binding pair.
| Entry | Binding pair | Kd (μM) |
|---|---|---|
| 1 | RRM1 – AUG12 | 0.48 ± 0.09 |
| 2 | RRM2 – AUG12 | >30 |
| 3 | RRM1-2 – AUG12 | 0.0039 ± 0.0009 |
| 4 | RRM1 – NegAUG12 | 2.55 ± 0.48 |
| 5 | RRM2 – NegAUG12 | N.D |
| 6 | RRM1-2 – NegAUG12 | 2.6 ± 0.6 |
The values are all expressed in μM for conformity.
