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. 2018 Sep 25;9:1336. doi: 10.3389/fphys.2018.01336

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Copyright © 2018 Brown, Foletta, Wright, Sepulveda, Konstantopoulos, Sanigorski, Della Gatta, Cameron-Smith, Kralli and Russell.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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mRNA expression of genes identified from the microarray based on their GO terms involved with protein synthesis, translation, and growth. Myotubes were infected with GFP, PGC-1α, or PGC-1β adenoviruses for 48 h, and samples were extracted after 72 h. mRNA of biasedly selected genes that were (A) upregulated and (B) downregulated in the microarray. mRNA expression of the genes selected unbiasedly from the microarray that were most significantly (C) upregulated and (D) downregulated. Values were normalized to 36B4 mRNA expression. n = 3, repeated in three experiments. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001 vs. GFP.