Figure 2.
Depression-like behavior in different groups. (A) The total distance of movement reduced in the DSS, stress, and comorbidity groups in OFT. (B) In center frequency reduction in the comorbidity group in OFT. (C,D) Increased immobility time in the FST and TST in DSS, stress, and comorbidity groups. (E) Decreased sucrose preference in 24 h in the comorbidity group. (F) No difference on total fluid consumption in 24 h. (G,H) Correlation analysis of mechanical allodynia and visceral hypersensitivity with immobility time in FST. Statistical comparisons were performed with one-way ANOVA followed by Dunnett's t-test and two-way ANOVA followed by post hoc Bonferroni. *p < 0.05, **p < 0.001, compared with the naïve group; OFT, open field test; FST, forced swim test; TST, tail suspension test; SPT, sucrose preference test.
