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. 2018 Oct 9;12:234. doi: 10.3389/fnbeh.2018.00234

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Copyright © 2018 Qing, Li, Wang, Quan, Ouyang and Liao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Inhibiting RIP1 using necrostatin-1 on neuroplasticity. (A) Representative pictures of DCX+ cells in the dentate gyrus (DG). DCX+ cells were counted in the subgranular zone (SGZ) of the entire DG. Scale bar = 50 μm. Data are expressed as the mean ± standard error of mean (SEM). ^∗p < 0.05; ^∗∗p < 0.01; (n = 3, one-way ANOVA followed by Turkey’s post hoc comparisons tests). (B) qPCR analysis of mRNA levels of NMDA receptors (NR1, NR2A, and NR2B) and AMPA receptors (GluA1 and GluA2) in the hippocampus. Data are expressed as the mean ± SEM. ^∗p < 0.05; ^∗∗p < 0.01; (n = 4, one-way ANOVA followed by Turkey’s post hoc comparisons tests).