Table 1.
Distribution of PD-1 and PD-L1 expression on immune cell subpopulations.
| PD-1 | PD-L1 | |||
|---|---|---|---|---|
| Cell frequency, % | MFI | Cell frequency, % | MFI | |
| CD3−NK1.1+CD4− | 4.02 (±1.35) | 992.6 (±407.4) | n.d. (not detected) | n.d. |
| CD3+NK1.1+CD4+ | 22.55 (±12.98) | 2,308 (±298.2) | n.d. | n.d. |
| CD11chighCD11b+ | n.d. | n.d. | 91.73 (±4.44) | 22,500 (±25.5) |
| CD11cintCD45R+ | n.d. | n.d. | 58.3 (±14.79) | 5,913 (±233.3) |
| CD11b+Gr-1−F4/80+ | n.d. | n.d. | 82.3 (±0.63) | 9,223 (±70) |
| CD11b+Gr-1+ | n.d. | n.d. | 21.58 (±11.69) | 7,669 (±2,250) |
| CD11b+Gr-1highLy-6Cint | n.d. | n.d. | 15.27 (±6.99) | 4,040 (±2,329) |
| CD11b+Gr-1intLy-6Chigh | n.d. | n.d. | 44 (±10.52) | 6,772 (±1,539) |
| CD8+CD3+ | 11.16 (±6.72) | 1,103 (±437.7) | 81 (±26.73) | 683 (±49.5) |
| CD62L−CD44+CD8+ | n.d. | n.d. | 1.34 (±0.26) | 993 (±162.6) |
| CD62L+CD44+CD8+ | n.d. | n.d. | 64.65 (±0.26) | 876 (±86.3) |
| CD62L+CD44−CD8+ | n.d. | n.d. | 83.35 (±0.26) | 554 (±22.6) |
| CD62L−CD44−CD8+ | n.d. | n.d. | 1.47 (±0.26) | 671 (±166.9) |
| CD4+CD3+ | 14.54 (±4.88) | 1,468 (±429.3) | 57.87 (±27.65) | 1,568 (±1,686) |
| CD62L−CD44+CD4+ | n.d. | n.d. | 85.8 (±6.79) | 1,490 (±16.3) |
| CD62L+CD44+CD4+ | n.d. | n.d. | 44.05 (±7.99) | 1,688 (±359.9) |
| CD62L+CD44−CD4+ | n.d. | n.d. | 48.75 (±40.94) | 801 (±14.1) |
| CD62L−CD44−CD4+ | n.d. | n.d. | 41.9 (±40.94) | 1,494 (±304.1) |
| CD25dimFoxP3+CD4+ | 39.18 (±9.83) | 2,226 (±343.5) | 54.3 (±40.94) | 3,156 (±2,771) |
| CD25+FoxP3+CD4+ | 24.15 (±6.65) | 2,213 (±355.8) | 84.45 (±9.12) | 3,223 (±2,785) |
| CD25+FoxP3−CD4+ | 18.68 (±7.59) | 1,654 (±266.4) | 4.2 (±5.06) | 2,632 (±2,722) |
| CD25−FoxP3−CD4+ | 77.07 (±2.74) | 1,400 (±187.3) | 70.25 (±0.64) | 2,583 (±2,786) |