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. 2018 Oct 9;9:404. doi: 10.3389/fgene.2018.00404

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Copyright © 2018 Iancu, Boutros, Olsen, Davis, Stewart, Eiwaz, Marzulla, Belknap, Fallgren, Edmondson, Weil and Raber.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exposure to ionizing radiation results in large shifts in the patterns of genetic influence over cognitive performance. Odds ratios below 1 signify that there is no overlap between the markers detected under sham versus ionizing radiation conditions. This lack of concordance in the identity of significant markers is detected in both the 600 cohort (A) and 1,200 cohort (B). Only two phenotypes show concordance between sham and ionizing radiation: train_avgmo (both cohorts) and context_avgmo (1,200 cohort). Black filled squares represent confidence intervals of the Fisher exact test, with values < 1 showing lack of significant overlap.