Figure 5.

Oligodendrocyte HOG cell death due to treatment with sphingosine.

HOG cells were cultured and incubated with various concentration of sphingosine. Cells were incubated for 24 h and the viability was measured using cell-counting kit. An initial stimulation of growth of the cultured HOG cells was observed at a low concentration of sphingosine while a higher concentration of sphingosine stimulated cell death. The bar graph represents a set of three individual experiments. An asterisk (*) indicates a p value of <0.05.