Figure 2.

Adiponectin modulates FA assembly in vivo. A) Desmin and vinculin staining of liver sections from WT and Ad^−/− mice. Confocal images reveal increased vinculin and desmin staining in liver sections from CCl₄-treated mice. Ad-LacZ fails to reduce staining intensity; however, Ad-Adn in CCl₄-gavaged mice markedly attenuates vinculin and desmin staining. B) Confocal images of p-FAK and desmin from liver sections of WT and Ad^−/− mice. In CCl₄-gavaged mice, p-FAK and desmin staining increased, but following Ad-Adn rescue, staining intensity was markedly reduced. Scale bars = 50 μm (n≥4 mice/cohort).