Table 2. Mechanical withdrawal thresholds of rats in normal, knee osteoarthritis, and knee osteoarthritis-antagonist groups.
Group (n=15) | Preoperative | 14th day | 28th day | 42nd day | 56th day |
Mean±SEM | Mean±SEM | Mean±SEM | Mean±SEM | Mean±SEM | |
Normal | 12.667±7.090 | 14.000±9.295 | 17.833±6.616 | 12.500±7.148 | 22.333±5.680 |
Knee osteoarthritis | 13.167±6.706 | 4.667±2.733** | 3.667±1.506** | 6.000±2.828** | 6.000±2.191** |
Antagonist | 13.667±6.831 | 6.333±2.338△ | 11.167±4.446△△ | 12.333±4.179△△ | 15.500±8.526△△ |
SEM: Standard error of the mean; * p<0.05; ** p<0.01, compared with normal group; △ p<0.05, △△ p<0.01, compared with the knee osteoarthritis group. |