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JNK1−/− mice display sustained protection against HFD-induced steatosis, but not against liver inflammation. A) Hematoxylin and eosin staining of representative liver sections of 44-wk-old WT mice and JNK1−/− mice kept on an HFD. B) F4/80 immunostaining of liver sections from the same mice. C) Quantification of the number of F4/80+ cells from the liver sections in (B). D) Real-time qPCR analysis of the expression of proinflammatory genes in mouse liver.
