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. 2018 Oct 16;13(10):e0205709. doi: 10.1371/journal.pone.0205709

Table 4. The associated factors of high LDL-C among T2DM (9285).

Antihyperlipidemic medication
No (n = 8461) Yes (824)
Gender (women vs. men) 1.69 (1.39–2.05) *** 1.93 (1.25–3.00) **
Area (rural vs. urban) 0.90 (0.65–1.26) 0.87 (0.45–1.69)
Age, years
 45–54 1.00 (ref) 1.00 (ref)
 55–64 1.36 (1.13–1.63) *** 1.06 (0.59–1.90)
 65–74 1.24 (0.99–1.57) 1.09 (0.51–2.35)
 ≥75 1.28 (0.97–1.69) 2.77 (0.95–8.06)
P-trend 0.03 0.19
Education
 Uneducated 1.00 (ref) 1.00 (ref)
 Primary school 1.33 (1.02–1.74) * 0.63 (0.30–1.31)
 Junior school 1.03 (0.77–1.37) 0.39 (0.17–0.91) *
 High school 1.43 (1.06–1.94) * 0.65 (0.26–1.66)
 College and above 1.43 (0.96–2.12) 0.44 (0.17–1.14)
P-trend 0.19 0.34
Smoking
 Never smoker 1.00 (ref) 1.00 (ref)
 Current smoker 1.00 (0.84–1.19) 0.90 (0.44–1.87)
 Former smoker 1.42 (1.05–1.93) * 0.97 (0.42–2.25)
Drinking
 Never drinker 1.00 (ref) 1.00 (ref)
 Moderate alcohol drinker 1.31 (1.01–1.69) * 0.92 (0.52–1.62)
 Excessive alcohol drinker 0.98 (0.73–1.33) 1.44 (0.43–4.83)
Physical activity
 Low 1.00 (ref) 1.00 (ref)
 Moderate 1.13 (0.97–1.32) 1.43 (0.77–2.66)
 High 1.01 (0.83–1.23) 0.97 (0.59–1.59)
 Very high 1.09 (0.87–1.37) 0.67 (0.29–1.53)
P-trend 0.63 0.43
Obesity (yes vs. no) 1.34 (0.99–1.82) 0.70 (0.31–1.62)
Abdominal obesity (yes vs. no) 0.89 (0.75–1.06) 1.56 (0.77–3.15)
Hypertension (yes vs. no) 0.96 (0.80–1.15) 0.95 (0.41–2.16)

Abbreviations: BMI, body mass index.

Adjusted for the sex, age, area, smoking status, drinking status, physical activity level, BMI, abdominal obesity, and hypertension. Except the variable of interest.

*: P < 0.05

**: P < 0.01

***: P < 0.001