Table 2.
Kidney Transplant Recipient and Allograft Characteristics, Stratified by Preemptive Listing Status and Transplant in Pre- or Post- Kidney Allocation System Period
| Pre-KAS December 4, 2011-December 3, 2014 |
Post-KAS December 4, 2014-December 3, 2017 |
|||||
|---|---|---|---|---|---|---|
| Not Preemptively Listed | Preemptively Listed | p-valuea | Not Preemptively Listed | Preemptively Listed | p-valueb | |
| 22844 | 7282 | 28845 | 6414 | |||
| Race/Ethnicity | <0.001 | <0.001 | ||||
| White | 8455 (37.0%) | 4405 (60.5%) | 9109 (31.6%) | 3684 (57.4%) | ||
| Black | 8112 (35.5%) | 1559 (21.4%) | 11094 (38.5%) | 1398 (21.8%) | ||
| Hispanic | 4212 (18.4%) | 653 (9.0%) | 5885 (20.4%) | 709 (11.1%) | ||
| Other | 2065 (9.0%) | 665 (9.1%) | 2757 (9.6%) | 623 (9.7%) | ||
| Age (years) | 55.0 (44.0, 63.0) | 58.0 (49.0, 65.0) | <0.001 | 53.0 (42.0, 62.0) | 57.0 (46.0, 65.0) | <0.001 |
| Sex | <0.001 | <0.001 | ||||
| Female | 8608 (37.7%) | 3227 (44.3%) | 11117 (38.5%) | 3133 (48.8%) | ||
| Male | 14236 (62.3%) | 4055 (55.7%) | 17728 (61.5%) | 3281 (51.2%) | ||
| Waiting Time (from Listing to Transplant) | <0.001 | <0.001 | ||||
| <1 Year | 5627 (24.6%) | 1094 (15.0%) | 10708 (37.1%) | 1339 (20.9%) | ||
| 1–2.9 Years | 8208 (35.9%) | 2715 (37.3%) | 8809 (30.5%) | 1865 (29.1%) | ||
| >3 Years | 9009 (39.4%) | 3473 (47.7%) | 9328 (32.3%) | 3210 (50.0%) | ||
| Prior Donor | 0.022 | <0.001 | ||||
| No | 22772 (99.7%) | 7245 (99.5%) | 28781 (99.8%) | 6355 (99.1%) | ||
| Yes | 71 (0.3%) | 36 (0.5%) | 58 (0.2%) | 57 (0.9%) | ||
| Missing | 1 (<1%) | 1 (<1%) | 6 (<1%) | 2 (<1%) | ||
| Private Insurance | <0.001 | <0.001 | ||||
| No | 15059 (65.9%) | 2574 (35.3%) | 20923 (72.5%) | 2319 (36.2%) | ||
| Yes | 7784 (34.1%) | 4705 (64.6%) | 7919 (27.5%) | 4093 (63.8%) | ||
| Missing | 1 (<1%) | 3 (<1%) | 3 (<1%) | 2 (<1%) | ||
| Education | <0.001 | <0.001 | ||||
| Less than High School | 1923 (8.4%) | 274 (3.8%) | 2448 (8.5%) | 235 (3.7%) | ||
| High School Graduate | 15676 (68.6%) | 4532 (62.2%) | 19732 (68.4%) | 3935 (61.4%) | ||
| College Graduate or Higher | 4576 (20.0%) | 2237 (30.7%) | 5854 (20.3%) | 2047 (31.9%) | ||
| Missing/Unknown | 669 (2.9%) | 239 (3.3%) | 811 (2.8%) | 197 (3.1%) | ||
| KDPI | 0.26 | <0.001 | ||||
| >20 | 18454 (80.8%) | 5836 (80.1%) | 23519 (81.5%) | 4884 (76.1%) | ||
| <20 | 4369 (19.1%) | 1436 (19.7%) | 5325 (18.5%) | 1530 (23.9%) | ||
| Missing | 21 (0.1%) | 10 (0.1%) | 1 (<1%) | 0 (0.0%) | ||
| Zero Antigen Mismatch | 1796 (7.9%) | 731 (10.0%) | <0.001 | 1177 (4.1%) | 549 (8.6%) | <0.001 |
| Prior Transplant | 2846 (12.5%) | 1024 (14.1%) | <0.001 | 4197 (14.6%) | 1018 (15.9%) | 0.007 |
| Diabetic | <0.001 | <0.001 | ||||
| No | 13832 (60.5%) | 4993 (68.6%) | 18334 (63.6%) | 4689 (73.1%) | ||
| Yes | 8962 (39.2%) | 2261 (31.0%) | 10484 (36.3%) | 1716 (26.8%) | ||
| Missing | 50 (0.2%) | 28 (0.4%) | 27 (0.1%) | 9 (0.1%) | ||
| BMI Category (kg/m2) | <0.001 | 0.003 | ||||
| 18.5–24.9 | 6193 (27.1%) | 2019 (27.7%) | 8420 (29.2%) | 1859 (29.0%) | ||
| <18.5 | 384 (1.7%) | 95 (1.3%) | 493 (1.7%) | 115 (1.8%) | ||
| 25–29.9 | 7757 (34.0%) | 2516 (34.6%) | 9589 (33.2%) | 2218 (34.6%) | ||
| 30–39.9 | 8039 (35.2%) | 2552 (35.0%) | 9889 (34.3%) | 2159 (33.7%) | ||
| >40 | 471 (2.1%) | 100 (1.4%) | 454 (1.6%) | 63 (1.0%) | ||
| HIV Positive | <0.001 | <0.001 | ||||
| No | 21062 (92.2%) | 6788 (93.2%) | 27476 (95.3%) | 6211 (96.8%) | ||
| Yes | 226 (1.0%) | 25 (0.3%) | 499 (1.7%) | 29 (0.5%) | ||
| Unknown | 1556 (6.8%) | 469 (6.4%) | 870 (3.0%) | 174 (2.7%) | ||
| HCV Positive | <0.001 | <0.001 | ||||
| No | 21475 (94.0%) | 7008 (96.2%) | 26843 (93.1%) | 6058 (94.4%) | ||
| Yes | 1263 (5.5%) | 239 (3.3%) | 1920 (6.7%) | 333 (5.2%) | ||
| Unknown | 106 (0.5%) | 35 (0.5%) | 82 (0.3%) | 23 (0.4%) | ||
| Blood Group | <0.001 | <0.001 | ||||
| A | 7849 (34.4%) | 2731 (37.5%) | 9604 (33.3%) | 2513 (39.2%) | ||
| A1 | 251 (1.1%) | 87 (1.2%) | 287 (1.0%) | 62 (1.0%) | ||
| A1B | 22 (0.1%) | 6 (0.1%) | 32 (0.1%) | 14 (0.2%) | ||
| A2 | 36 (0.2%) | 21 (0.3%) | 32 (0.1%) | 11 (0.2%) | ||
| A2B | 6 (<1%) | 0 (0.0%) | 9 (<1%) | 4 (0.1%) | ||
| AB | 1165 (5.1%) | 405 (5.6%) | 1418 (4.9%) | 415 (6.5%) | ||
| B | 3037 (13.3%) | 885 (12.2%) | 3908 (13.5%) | 836 (13.0%) | ||
| O | 10478 (45.9%) | 3147 (43.2%) | 13555 (47.0%) | 2559 (39.9%) | ||
| Calculated PRA | 0.0 (0.0, 44.0) | 0.0 (0.0, 41.0) | 0.57 | 0.0 (0.0, 59.0) | 0.0 (0.0, 70.0) | <0.001 |
|
| ||||||
Abbreviations: KAS—kidney allocation system; ECD—expanded criteria donor; DCD—donation after circulatory determination of death; cPRA—calculated panel reactive antibody
Values presented as median (interquartile range) and n (%)
a
p-values comparing non-missing data from Chi-Square Tests and Wilcoxon Rank Sum Tests, as appropriate among recipients in pre-KAS period
b
p-values comparing non-missing data from Chi-Square Tests and Wilcoxon Rank Sum Tests, as appropriate among recipients in post-KAS period