Cisplatin treatment increased reactive oxygen species in zebrafish sensory endorgans. A.-B. Endorgan treatment labeling: saccule-cisplatin (S-C), saccule-vehicle (S-V), utricle-cisplatin (U-C), utricle-vehicle (U-V). A. 100 µM cisplatin (dark gray) treatment increased ROS in tissue samples compared to vehicle (white) treatment. B. 500 µM cisplatin (dark gray) treatment increased ROS in tissue samples compared to vehicle (white) treatment. RFU = relative fluorescence units. N = 3–6; “*”, p < 0.05; “***”, p < .001; “****”, p < 0.0001.