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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Breast Cancer Res Treat. 2018 Jul 30;172(1):83–91. doi: 10.1007/s10549-018-4902-z

Table 2.

Sensitivity, specificity, and predictive value analyses compared to perometry (%).

Detection of RVC > 10% Detection of RVC 5–10%
SN
(%)
SP
(%)
PPV
(%)
NPV
(%)
SN
(%)
SP
(%)
PPV
(%)
NPV
(%)
4-cm intervals 81.9 68.4 46.5 91.9 16.0 91.5 40.0 75.5
    BMI < 25 (n = 96) 71.4 74.7 44.1 90.3 13.0 84.9 21.4 75.6
    BMI 25–30 (n = 94) 85.0 64.9 39.5 94.1 21.7 95.8 62.5 79.1
    BMI > 30 (n = 97)
87.1
63.5
54.0
90.9
11.1
94.0
42.9
72.4
4-cm intervals, end correction 77.8 92.6 77.8 92.6 52.0 82.5 51.3 82.9
    BMI < 25 (n = 96) 71.4 93.3 75.0 92.1 47.8 79.5 42.3 82.9
    BMI 25–30 (n = 94) 85.0 98.6 94.4 96.1 69.6 87.3 64.0 89.9
    BMI > 30 (n = 97)
77.4
85.7
72.7
88.5
40.7
80.6
45.8
77.1
Landmarks 93.1 93.5 82.7 97.6 63.2 93.8 78.7 87.6
    BMI < 25 (n = 96) 90.5 94.7 82.6 97.3 60.9 94.5 77.8 88.5
    BMI 25–30 (n = 94) 90.0 91.9 75.0 97.1 58.3 90.0 66.7 86.3
    BMI > 30 (n = 97)
96.8
93.7
88.2
98.3
66.7
97.0
90.0
87.8
Landmarks, midpoint 90.3 93.5 82.3 96.6 66.7 90.1 70.4 88.4
    BMI < 25 (n = 96) 81.0 94.7 81.0 94.7 73.9 90.4 70.8 91.7
    BMI 25–30 (n = 94) 95.0 93.2 79.2 98.6 56.5 90.1 65.0 86.5
    BMI > 30 (n = 97) 93.5 93.7 87.9 96.7 70.4 91.0 76.0 88.4

Abbreviations: BMI, body mass index; NPV, negative predictive value; PPV, positive predictive value; RVC, relative volume change; SN, sensitivity; SP, specificity.