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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Dev Biol. 2018 Aug 25;443(1):50–63. doi: 10.1016/j.ydbio.2018.08.011

Table 2.

RNAseq of distal tip lung mesenchyme from E10.5 embryos.

Gene Folds p-value Gene name
Wnt signaling pathway
Wnt2 −2.17 1.07E-14 Wnt family member 2
Wnt 11 −2.14 2.67E-07 Wnt family member 11
Nog −1.94 0.0062 Noggin
Trpm4 −1.92 7.64E-06 Transient receptor potential cation channel, subfamily M, member 4
Nkd2 −1.90 0.00026 Naked cuticle homolog 2
Biccl −1.83 1.55E-13 BicC family RNA binding protein 1
Isl1 −1.82 9.96E-06 ISL LIM homeobox 1
Snai2 −1.79 0 Snail family zinc finger 2
Wnt5a −1.77 0.0006 Wnt family member 5A
Siah2 −1.71 0.0043 Siah E3 ubiquitin protein ligase 2
Zfp703 −1.65 0.0006 Zinc finger protein 703
Rspo1 −1.59 4.44E-11 R-spondin 1
Wif1 4.87 0 Wnt inhibitory factor 1
Regulation of smooth muscle proliferation and differentiation
Cdh13 −10.7 0 Cadherin13
Hoxb7 −10.47 2.72E-10 Homeobox B7
Trpc3 −4.62 5.77E-15 Transient receptor potential cation channel subfamily C member 3
Calcb −3.98 0.00028 Calcitonin related polypeptide beta
Cacna1c −3.81 0 Calcium voltage-gated channel subunit alpha 1C
Kcnb2 −2.95 1.75E-11 Potassium voltage-gated channel subfamily B member 2
Twist2 −2.52 1.18E-08 Twist family bHLH transcription factor 2
Actg2 −2.27 0.0024 Gamma2 actin
Hand2 −2.24 0.0067 Heart and neural crest derivatives expressed 2
Edn3 −2.07 2.8E-6 Endothelin 3
Egfr −2.05 0 Epidermal growth factor receptor
Gucy1a3 −1.84 0 Guanylate cyclase 1 soluble subunit alpha
Chrm3 −1.77 0.011 Cholinergic receptor muscarinic 3
Igf1 −1.7 0 Insulin like growth factor 1
Klf4 −1.68 1.77E-05 Kruppel like factor 4
Cald1 −1.63 0 Caldesmon 1
Cardiovascular system development
Bmp4 1.86 0 Bone morphogenic protein 4
Tnnt2 2.12 1.11E-16 Troponin T2, cardiac type
Tnni3 2.9 2.31E-05 Troponin I3, cardiac type
Tnni1 3.46 0 Troponin I1, slow skeletal; cardiac during embryonic development
Tnnc1 5.09 7.24E-13 Troponin C1, slow skeletal and cardiac type
Csrp3 13.26 0 Cysteine and glycine rich protein 3