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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Am Soc Mass Spectrom. 2018 Jul 25;29(11):2182–2188. doi: 10.1007/s13361-018-2028-5

Figure 5.

Figure 5.

Interferences increase at lower concentrations in the all-ions fragmentation spectra when IMS filtering is not utilized. LC-CID-MS spectra for the transition ions of SLHTLFGDELC[+57]K2+ are shown at 100 pM A) without and B) with IMS filtering. The plots on the right of each XIC show two ions co-eluting in the LC dimension, but being separated by IMS. The transition of interest occurs at 29 ms, while the interfering ion is at 33 ms, causing noise around the transitions if IMS filtering is not utilized.