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. Author manuscript; available in PMC: 2019 Oct 15.
Published in final edited form as: Cancer Res. 2018 Aug 16;78(20):5992–6000. doi: 10.1158/0008-5472.CAN-18-0447

Figure 5. Efficacy of MV on tumor control and in vivo correlations.

Figure 5.

(A)Tumor growth was measured by serial caliper data. Untreated tumor xenografts grew the fastest. MV-NIS did slow down tumor growth but the effect was maximal for MV-I98A-NIS showing that at least in this model, faster replication may not result in a better outcome. (B) A positive correlation (ρ = 0.4475, p = 0.02) between viable virus isolated from excised tumors and the intratumoral isotope activity determined by imaging data from 26 mice is illustrated.