Table 2.
Baseline Disease Characteristics by BMI Group*
| BMI < 25 (L) N=175 |
BMI 25-30 (M) N=84 |
BMI ≥ 30 (H) N=64 |
Kruskal-Wallis p-value |
Pairwise Comparisons | ||||
|---|---|---|---|---|---|---|---|---|
| Median | IQR | Median | IQR | Median | IQR | |||
| ACR CORE SET MEASURES | ||||||||
| Patient Global | 57 | 41 | 53 | 46 | 57 | 38 | 0.87 | |
| Physician Global | 48 | 37 | 46 | 27 | 55 | 26 | 0.03 | M<H |
| HAQ-DI | 1.13 | 0.88 | 1.00 | 1.13 | 1.38 | 0.88 | 0.02 | L<H, M<H |
| Pain | 61 | 44 | 61 | 35 | 69 | 43.5 | 0.35 | |
| ESR | 35 | 28 | 35 | 34 | 40 | 30 | 0.65 | |
| Tender 28 | 12 | 12 | 12 | 10 | 12 | 14.5 | 0.52 | |
| Tender 44 | 18 | 15 | 18 | 15 | 19 | 22 | 0.60 | |
| Swollen 28 | 11 | 11 | 11 | 10 | 14 | 13.5 | 0.06 | |
| Swollen 44 | 16 | 12 | 16 | 14 | 20 | 18 | 0.009 | L<H, M<H |
| DISEASE MEASURES | ||||||||
| CDAI | 32.6 | 21.0 | 32.6 | 15.6 | 37.2 | 28.4 | 0.13 | |
| DAS28/ESR4 item | 6.08 | 1.77 | 6.15 | 1.21 | 6.26 | 1.71 | 0.15 | |
| DAS44/ESR4 item | 4.47 | 1.65 | 4.45 | 1.78 | 4.86 | 2.00 | 0.02 | L<H, M<H |
| UPPER EXTREMITIES (UE) | ||||||||
| UE Swollen | 11 | 10 | 11 | 10 | 14 | 12 | 0.12 | |
| Shoulder Swollen | 0 | 0 | 0 | 0 | 0 | 0 | 0.30 | |
| Elbow Swollen | 0 | 1 | 0 | 0 | 0 | 1 | 0.35 | |
| Wrist Swollen | 2 | 1 | 2 | 2 | 2 | 1 | 0.16 | |
| MCP Swollen | 5 | 5 | 5 | 6 | 6 | 6 | 0.02 | L<H |
| PIP Swollen | 5 | 6 | 5 | 6 | 5 | 8 | 0.56 | |
| LOWER EXTREMITIES (LE) | ||||||||
| LE Swollen | 5 | 7 | 4 | 6 | 8 | 9 | <0.001 | L<H, M<H |
| Knee Swollen | 0 | 1 | 0 | 2 | 1 | 2 | <0.001 | L<H, M<H |
| Ankle Swollen | 0 | 2 | 0 | 2 | 2 | 1 | <0.001 | L<H, M<H |
| MTP Swollen | 4 | 6 | 2 | 7 | 7 | 9 | 0.01 | M<H |
*
IQR = interquartile range, BMI = body mass index, HAQ-DI = health assessment questionnaire-disability index, ESR = erythrocyte sedimentation rate, CDAI = Clinical Disease Activity Index, DAS = Disease Activity Score, MCP = metacarpophalangeal joint, PIP = proximal interphalangeal joint, MTP = metatarsophalangeal joint