Table 4. Genetic findings of MSA-TDP compared to MSA.
TDP-positive N = 12 | TDP-negative N = 153 | P value | |
---|---|---|---|
GRN, T allele | 9/24 (38%) | 95/304 (31%) | 0.685 |
T/T | 3/12 (25%) | 12/152 (8%) | 0.101 |
T/C | 3/12 (25%) | 71/152 (47%) | |
C/C | 6/12 (25%) | 69/152 (45%) | |
TMEM106B, G allele | 7/24 (29%) | 124/306 (41%) | 0.380 |
G/G | 0/12 (0%) | 27/153 (18%) | 0.366 |
G/C | 7/12 (58%) | 70/153 (46%) | |
C/C | 5/12 (42%) | 56/153 (37%) |
Genetic analysis is performed for TDP-positive (N = 12) and TDP-negative (N = 153), respectively.