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. Author manuscript; available in PMC: 2020 Jan 1.

Published in final edited form as: J Magn Reson Imaging. 2018 Apr 16;49(1):176–183. doi: 10.1002/jmri.26046

Plots of actual versus quantified GSH levels from phantoms with varying concentrations of GSH are shown for each of the 4 sequences: SPECIAL ( ), PR-STEAM ( ), PRESS ( ), and MEGA-PRESS (▼). At higher GSH levels, the sequences were similar in their ability to detect GSH. From the 0mM GSH phantom, MEGA-PRESS was the only sequence to report 0mM while the other non-edited sequences reported trace levels of GSH. The linear regressions for SPECIAL, MEGA-PRESS and PR-STEAM were similar such that MEGA-PRESS and PR-STEAM linear regression lines overlapped. Overall, linear fits to the data were excellent with R² values of 0.996, 0.995, 0.987, and 0.998, respectively.

Inline graphic — Plots of actual versus quantified GSH levels from phantoms with varying concentrations of GSH are shown for each of the 4 sequences: SPECIAL ( ), PR-STEAM ( ), PRESS ( ), and MEGA-PRESS (▼). At higher GSH levels, the sequences were similar in their ability to detect GSH. From the 0mM GSH phantom, MEGA-PRESS was the only sequence to report 0mM while the other non-edited sequences reported trace levels of GSH. The linear regressions for SPECIAL, MEGA-PRESS and PR-STEAM were similar such that MEGA-PRESS and PR-STEAM linear regression lines overlapped. Overall, linear fits to the data were excellent with R² values of 0.996, 0.995, 0.987, and 0.998, respectively.