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. 2018 Oct 16;9:4282. doi: 10.1038/s41467-018-06727-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Design of the CALM system. a Operating CALM system with a cellphone optical accessory and a disposable microchip. b Exploded 3D schematic of the cellphone attachment. The main components of the cellphone attachment including a casting stage with optics, sample holder, and back cover with LED was printed using PLA. c Motion tracking application used to detect and measure the motion of DNA-motors in H₂O₂ solution. d Correlation between the performance of the motion tracking application and bright-field light microscopy coupled with the ImageJ software in velocity detection of different motor samples (n = 50). R² is the coefficient of determination of the linear regression analysis