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IGF-1 and BX795 enhance rod development in a PKC-dependent manner. Quantification (top) and representative images (bottom) of rhodopsin (green) and Hoechst-33258 (blue) labeled retinal explants following a 96-h exposure to nothing (controls) or (A) 50 nM IGF-1, 100 nM Go7874, or both; (B) 100 nM Go7874, 100 nM BX795, or both. n = 3 biological replicates/measure. ∗p < 0.05 and ∗∗∗p < 0.001.
