Table 1.
Reagents used in this study.
| Reagent | Action | Conc. | Catalog No. | Supplier |
|---|---|---|---|---|
| Insulin-like growth factor 1 (IGF-1) | IGF-1-R activator | 50 μg/mL | I8779 | Sigma |
| BX795 | PDPK-1 inhibitor (Feldman et al., 2005) | 100 nM | Tlrl-bx7 | InvivoGen |
| Go 7874 | PKC inhibitor | 50 nM | 365252 | EMD Millipore |
| KU0063794 | mTORC1/2 inhibitor (García-Martínez et al., 2009) | 100 nM | 3725 | Tocris |
| PF4708671 | P70-S6K inhibitor (Pearce et al., 2010) | 200 nM | 4032 | Tocris |
| Rapamycin | mTORC1 inhibitor (Sehgal, 2003) | 10 nM | 9904 | Cell signaling |
| GSK2334470 | PDPK-1 inhibitor (Najafov et al., 2011) | 3 nM–1 μM | 4143 | Tocris |
| Stattic | STAT3 inhibitor | 50 μM | 573099 | EMD Millipore |
| Leukemia inhibitory factor (LIF) | JAK/STAT3 activator | 20 ng/mL | ESG1107 | EMD Millipore |