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. 2018 Oct 10;8:345. doi: 10.3389/fcimb.2018.00345

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Copyright © 2018 Tanabe, Tanabe, Santos, Martins, Araújo, Cavalcante, Lima, Câmara, Anderson, Yunusov and Bassi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of CHIKV lineages that are associated with recent outbreaks around the world before and after year 2000. Top: CHIKV cases reported in the XX century (1953–2000). Bottom: CHIKV cases reported recently (2001–2018). Only cases where the virus lineage was identified are shown. Orange icon–Asian lineage; green icon–East/Central/South African (ECSA) lineage; green icon with a white circle–ECSA strain with a mutation A226V in the E1 envelope glycoprotein, this strain is sometimes referred to as Indian Ocean lineage (Wahid et al., 2017).