Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 10;9:2293. doi: 10.3389/fimmu.2018.02293

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Knuhr, Langhans, Nyenhuis, Viertmann, Kildemoes, Doenhoff, Haas and Schramm.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Detection of IPSE/alpha-1 and basophils in schistosome egg granulomas. Sections of S. mansoni-infected murine liver were stained for IPSE/alpha-1 (anti-IPSE/alpha-1; A) and basophils (anti-mMCP-8; B). Depicted are two magnification, each. Scale bars are 200 μm for 100x magnification and 50 μm for 400x magnification. (a,b) Show small granulomas with presumably immature eggs without IPSE/alpha-1 production (Aa, left box, Ab) and with basophils detected near the egg (Ba,Bb). (c,d) Show advanced granulomas with strong IPSE/alpha-1 staining in the subshell area and outside the eggs (Ac right box, Ad) and with basophils detected mainly in the outer rim of the granuloma (Bc,d). (e,f) Show negative controls without the respective primary antibodies.