Figure 5.

NAc cell types display distinct passive and active properties. A, Whole-cell current-clamp recordings of D1+ (tdTomato+), D1− (tdTomato−), PV+ (PV-2A-Cre with AAV-DIO-EYFP), and SOM+ (SOM-Cre with AAV-DIO-EYFP) cells in the NAc medial shell at resting membrane potentials or in response to current injections. Scale bars = 200 ms, 20 mV. B, Graph of action potential firing in all cell types during 500 ms current injections across a range of intensities, with values shown as means ± SEM. C, Quantification of input resistance (left) and resting membrane potential (right) from all cell types, calculated using a 500 ms, −50 pA current injection and depicted as means ± SEM. Note that values for SOM+ cells include only cells that were not firing spontaneously.