Figure 4.

Regression plots for the functional imaging analyses. Partial residual plots for the four edges that explained the greatest percentage of variance (R² change) in RSA and SCL (controlling for age, sex, education, and diagnosis). Higher resting RSA was associated with (A) greater left vAI-left ACC (edge 2–5) and (B) lower left ACC-right hypothalamus (edge 7–19) functional connectivity. Higher SCL was associated with (C) greater left ACC-right hypothalamus (edge 6–19) and (D) lower right dAI-PAG (edge 11–21) functional connectivity. Given that we controlled for diagnosis in the regression models, these plots show that the association that we detected between edge connectivity and resting autonomic activity was present in both diagnostic groups and, thus, was not driven by group membership. When we repeated the original analyses in each diagnosis separately, RSA and SCL had similar associations with the functional connectivity measures (Figure 4-1). For other abbreviations, see Figure 1.